Not so much as far as I can see. I just did an inplace upgrade of Windows 7 over my Vista x64. I had to completely disable Windowblinds otherwise no programs would open. Now before you go assailing me with "its beta' I know that. I've been beta testing applications on Windows since 3.0 shipped so I understand. I'm not asking for help I'm trying to inform.
So far I have found that Bootskin Vista nad LogonStudio don't work either. I haven't yet isolated if the newer UAC has something to do with or if even the extra DEP in x64 is stopping things from working. Once i have a chance and time to dig further I will post what I find.
Cursor FX works like a charm. So far Icon Packager is good to go as well, though I did have to reapply after the upgrade.
So over the next few days (the upcoming weekend) I will start uninstalling and reinstalling things to see3 what works and what doesn't. If anyone in Stardock support and/or testing wished to coontact me feel free to do so as I am more than happy to try things and to reports findings. I am not, however running debug symbols and checked build.