Unfortunately, they have apparently lost their chance to have their cake and eat it too.
While Windows 8 is fine, nay competitive finally, on tablets and phones with touch, it's completely half-baked when it comes to desktop users.
From home to business users--the 95% market share MS has built up on the desktop--the invisible control gadgets, removal of the smart button, lack of close gadgets, etc. is going to confuse the hell out of the less techno-literate.
And MS didn't need to do this. If the necessary GUI options were provided and made the default for upgraders and/or non touch users (re: EVERYONE with a desktop computer for the past 30 years), home and business users would have had ONE thing to adapt to, Metro. There would have been bitching, of course, but the Start Menu->Start Screen is easy to grok if everything else works similarly.
Businesses will "skip" Windows 8 entirely and home users will switch to Apple out of their frustration--as Apple will be the only major commercial vendor providing consumers a viable and recognizable "windows" experience.