I want to let you all know about a cool non-profit that is doing great things: Kiva.org
Kiva.org allows individuals to make $25 loans or more to low-income entrepreneurs in the developing world (microfinance). By doing so, individuals like you provide affordable working capital for the poor (money to buy a sewing machine, livestock, etc.), empowering them to earn their way out of poverty.
It's a new, direct and sustainable way to fight global poverty, and the way I see it, I get a higher return on $25 helping someone build a future than the interest my checking account pays.
Anyways, if you have a minute, please check out the site: kiva.org
If you need more "reputable" validation than my recommendation, know that they have received great press in publications ranging from The Wall Street Journal to NPR to BusinessWeek. Moreover this week it was featured on CNN's Heroes program.
Thanks for reading!