From your screenshot you grouped few explorer linked to onedrive folders, yes? Does the same issue happen if you group local folders only.
I use other grouped programs ( Autocad, Foxit, Solibri, Virtualbox, PDF-Xcahnge, Excel, Word ) with Groupy, and I have no issue.
The problem seems to be only with windows explorer. I will try to put Chrome outside this group to see if it changes anything.
I have to kill windows explorer 6 or 7 times a day when it becomes too laggy, loading too much the processor.
It is especially sensible on my laptop, wich is slower than my desktop, but my laptop has already 32Go RAM, so it is not a memory problem. (4 core 8 thread processor)
I have the same issue with my desktop, but less sensible, because it is a Ryzen 9 5950X 16/32 core, so very fast, and with 32 threads it uses less processor capacity, as it is 4 times bigger and faster too.
If I put Groupy OFF, I have no problem using the same number of windows explorer, but I can't leave anymore without Groupy