That's too high of a bitrate for me. Anything over 18k uses up excessive CPU.
A few tips...
Unless you have a lot of motion, try to go with 25 fps to lower cpu usage.
Also, never change frame rate or use the filters in TMPGEnc4 as it will cause loop hesitation. Always do the editing in something like Adobe After Effects.
Try these setting, I get great results. I start with 10k for bitrate and work up to a max of 18k, depending on how the quality looks. The higher the bitrate, the better the quality but the trade off is higher cpu usage.
For "fair use video", bit rate can be higher since file size really isn't an issue, due to the video clip being 15 seconds or less.
For your renders, once you start going over 60 seconds you'll have to start finessing bitrate to keep your file size below the max.
Hope it helps.