The new update to MyColors caused a conflict with current installs of WindowBlinds. We are working on a fix right now for this problem and will post it right away.
In the mean time here is the current work around if you have updated MyColors and are now unable to skin (would only apply if you had WindowBlinds installed as well).
-Updated MyColors (settings tab > update)
-Reboot your computer
-Reboot your machine again
This will clear the issue for you. In the mean time the developers are working hard to fix the update for MyColors overwriting certain WindowBlinds files. Sorry for the trouble in this matter and thank you for your patience.