- It doesn't work on disks using GPT. Which most newer systems should be using (it's required if you have UEFI and aren't running it in BIOS compatibility mode).
- I'd be surprised if booting to the repair console (via windows install disc) and running /fixmbr (assuming it still exists in newer versions of windows) didn't take care of it, since it rewrites the MBR.
- Booting from an optical disc will most definitely bypass it.
- It's only an extension of an APT ecosystem targeted at a specific bank. You won't be seeing it on your desktop, though of course someone else could come out with a bootkit malware targeted at consumers. They aren't a novel technique, and will still rely on some other malware, vulnerability, or social engineering to get themselves installed.